CRISPR

CRISPR2-nccr.dlx5i6

ID
ZDB-CRISPR-221017-9
Name
CRISPR2-nccr.dlx5i6
Previous Names
  • CRISPR1-dlx5a
Target
Sequence
5' - GGCTATTACAGCCCTGCCGG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM site was "AGG" at the 3' end.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
Df(19:nccr.dlx5i6,en.inter56)ot504 en.inter56, nccr.dlx5i6
ot502 dlx5a
Expression
Gene expression in Wild Types + CRISPR2-nccr.dlx5i6
No data available
Phenotype
Phenotype resulting from CRISPR2-nccr.dlx5i6
No data available
Phenotype of all Fish created by or utilizing CRISPR2-nccr.dlx5i6
Phenotype Fish Conditions Figures
pharyngeal arch 3-7 dlx2a expression increased amount, abnormal dlx5aot502/ot502 standard conditions Fig. 3 with image from Yu et al., 2021
telencephalon dlx2a expression increased amount, abnormal dlx5aot502/ot502 standard conditions Fig. 3 with image from Yu et al., 2021
ceratohyal cartilage malformed, abnormal dlx5aot502/ot502 standard conditions Figure 1 with image from Yu et al., 2023
brain dlx6a expression decreased amount, abnormal dlx5aot502/ot502 standard conditions Fig. 5 with image from Yu et al., 2021
palatoquadrate cartilage malformed, abnormal dlx5aot502/ot502 standard conditions Figure 1 with image,  Figure 2 with image from Yu et al., 2023
diencephalon dlx2a expression increased amount, abnormal dlx5aot502/ot502 standard conditions Fig. 3 with image from Yu et al., 2021
Meckel's cartilage malformed, abnormal dlx5aot502/ot502 standard conditions Figure 1 with image,  Figure 2 with image from Yu et al., 2023
palatoquadrate cartilage malformed, abnormal Df(19:nccr.dlx5i6,en.inter56)ot504/ot504 standard conditions Figure 1 with image,  Figure 2 with image from Yu et al., 2023
ceratohyal cartilage malformed, abnormal Df(19:nccr.dlx5i6,en.inter56)ot504/ot504 standard conditions Figure 1 with image from Yu et al., 2023
Meckel's cartilage malformed, abnormal Df(19:nccr.dlx5i6,en.inter56)ot504/ot504 standard conditions Figure 1 with image from Yu et al., 2023
Citations
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