CRISPR

CRISPR3-foxn1

ID

ZDB-CRISPR-230725-4

Name

CRISPR3-foxn1

Previous Names

None

Target

Sequence

5' - GGCCCTGAACCCAGCGAAGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
fr107	foxn1

Expression

Gene expression in Wild Types + CRISPR3-foxn1

No data available

Phenotype

Phenotype resulting from CRISPR3-foxn1

No data available

Phenotype of all Fish created by or utilizing CRISPR3-foxn1

Phenotype	Fish	Conditions	Figures
thymus pax9 expression increased amount, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. 1 , Fig. S1 from Schorpp et al., 2023
thymus rag1 expression decreased distribution, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. 2 from Schorpp et al., 2023
thymus trbc1 expression decreased amount, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. S1 from Schorpp et al., 2023
thymus foxn1 expression absent, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. 1 from Schorpp et al., 2023
thymus foxn4 expression decreased amount, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. 1 from Schorpp et al., 2023
thymus il7 expression decreased distribution, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. 2 from Schorpp et al., 2023
thymus trbc1 expression decreased distribution, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. 2 from Schorpp et al., 2023
thymus dll4 expression decreased distribution, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. 2 from Schorpp et al., 2023
whole organism lck expression decreased amount, abnormal	foxn1^fr107/fr107 (TU)	standard conditions	Fig. S1 from Schorpp et al., 2023
thymus EGFP expression decreased distribution, abnormal	foxn1^fr107/fr107; fr101Tg (TU)	standard conditions	Fig. 2 from Schorpp et al., 2023
pro-T cell decreased amount, abnormal	foxn1^fr107/fr107; fr101Tg (TU)	standard conditions	Fig. 2 from Schorpp et al., 2023

Citations