CRISPR

CRISPR1-vma21

ID
ZDB-CRISPR-250722-34
Name
CRISPR1-vma21
Previous Names
None
Target
Sequence
5' - GATGATAACTCTACCCAT - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
hsc227 vma21
hsc228 vma21
Expression
Gene expression in Wild Types + CRISPR1-vma21
No data available
Phenotype
Phenotype resulting from CRISPR1-vma21
No data available
Phenotype of all Fish created by or utilizing CRISPR1-vma21
Phenotype Fish Conditions Figures
liver lipid droplet increased amount, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 5 with image from Huang et al., 2025
muscle vacuole increased amount, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 4 with image from Huang et al., 2025
whole organism decreased length, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 2 with image from Huang et al., 2025
muscle lysosome organization decreased process quality, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 3 with image from Huang et al., 2025
xanthophore decreased distribution, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 2 with image from Huang et al., 2025
whole organism Ab6-map1lc3b labeling increased amount, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 4 with image from Huang et al., 2025
whole organism Ab1-vma21 labeling decreased amount, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 1 with image from Huang et al., 2025
gall bladder bile decreased amount, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 5 with image from Huang et al., 2025
whole organism dead, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 2 with image from Huang et al., 2025
swimming behavior decreased process quality, abnormal vma21hsc227/hsc227 (TU) chemical treatment by environment: optovin Figure 2 with image from Huang et al., 2025
swimming behavior decreased process quality, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 2 with image from Huang et al., 2025
muscle lysosome Ab2-lamp1 labeling decreased amount, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 3 with image from Huang et al., 2025
melanocyte decreased distribution, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 2 with image from Huang et al., 2025
swim bladder uninflated, abnormal vma21hsc227/hsc227 (TU) standard conditions Figure 2 with image from Huang et al., 2025
thigmotaxis process quality, ameliorated vma21hsc228/hsc228 (TU) chemical treatment by environment: LY294002 Figure 6 with image from Huang et al., 2025
whole organism viability, ameliorated vma21hsc228/hsc228 (TU) chemical treatment by environment: edaravone Figure 6 with image from Huang et al., 2025
thigmotaxis process quality, ameliorated vma21hsc228/hsc228 (TU) chemical treatment by environment: edaravone Figure 6 with image from Huang et al., 2025
muscle cell organization quality, ameliorated vma21hsc228/hsc228 (TU) chemical treatment by environment: edaravone Figure 6 with image from Huang et al., 2025
whole organism viability, ameliorated vma21hsc228/hsc228 (TU) chemical treatment by environment: LY294002 Figure 6 with image from Huang et al., 2025
xanthophore decreased distribution, abnormal vma21hsc228/hsc228 (TU) standard conditions Figure 2 with image from Huang et al., 2025
muscle lysosomal lumen acidification decreased process quality, abnormal vma21hsc228/hsc228 (TU) standard conditions Figure 3 with image from Huang et al., 2025
gall bladder bile decreased amount, abnormal vma21hsc228/hsc228 (TU) chemical treatment by environment: LY294002 Figure 6 with image from Huang et al., 2025
whole organism Ab1-vma21 labeling decreased amount, abnormal vma21hsc228/hsc228 (TU) standard conditions Figure 1 with image from Huang et al., 2025
whole organism Ab6-map1lc3b labeling increased amount, abnormal vma21hsc228/hsc228 (TU) standard conditions Figure 4 with image from Huang et al., 2025
gall bladder bile decreased amount, abnormal vma21hsc228/hsc228 (TU) control Figure 6 with image from Huang et al., 2025
thigmotaxis decreased process quality, abnormal vma21hsc228/hsc228 (TU) control Figure 6 with image from Huang et al., 2025
melanocyte decreased distribution, abnormal vma21hsc228/hsc228 (TU) standard conditions Figure 2 with image from Huang et al., 2025
swimming behavior decreased process quality, abnormal vma21hsc228/hsc228 (TU) standard conditions Figure 2 with image from Huang et al., 2025
gall bladder bile decreased amount, abnormal vma21hsc228/hsc228 (TU) chemical treatment by environment: edaravone Figure 6 with image from Huang et al., 2025
swimming behavior decreased process quality, abnormal vma21hsc228/hsc228 (TU) chemical treatment by environment: optovin Figure 2 with image from Huang et al., 2025
muscle cell organization quality, ameliorated vma21hsc228/hsc228 (TU) chemical treatment by environment: LY294002 Figure 6 with image from Huang et al., 2025
muscle cell disorganized, abnormal vma21hsc228/hsc228 (TU) control Figure 6 with image from Huang et al., 2025
swim bladder uninflated, abnormal vma21hsc228/hsc228 (TU) standard conditions Figure 2 with image from Huang et al., 2025
whole organism dead, abnormal vma21hsc228/hsc228 (TU) standard conditions Figure 2 with imageFigure 6 with image from Huang et al., 2025
xanthophore decreased distribution, abnormal vma21hsc227/+; vma21hsc228/+ (TU) standard conditions Figure 2 with image from Huang et al., 2025
whole organism Ab6-map1lc3b labeling increased amount, abnormal vma21hsc227/+; vma21hsc228/+ (TU) standard conditions Figure 4 with image from Huang et al., 2025
swimming behavior decreased process quality, abnormal vma21hsc227/+; vma21hsc228/+ (TU) chemical treatment by environment: optovin Figure 2 with image from Huang et al., 2025
melanocyte decreased distribution, abnormal vma21hsc227/+; vma21hsc228/+ (TU) standard conditions Figure 2 with image from Huang et al., 2025
swim bladder uninflated, abnormal vma21hsc227/+; vma21hsc228/+ (TU) standard conditions Figure 2 with image from Huang et al., 2025
swimming behavior decreased process quality, abnormal vma21hsc227/+; vma21hsc228/+ (TU) standard conditions Figure 2 with image from Huang et al., 2025
whole organism dead, abnormal vma21hsc227/+; vma21hsc228/+ (TU) standard conditions Figure 2 with image from Huang et al., 2025
Citations