ZFIN is now using GRCz12tu for Genomic Data
Gene
adgrl2a
- ID
- ZDB-GENE-000607-49
- Name
- adhesion G protein-coupled receptor L2a
- Symbol
- adgrl2a Nomenclature History
- Previous Names
-
- lphn2
- lphn2a
- id:ibd2808
- lphn2.1 (1)
- wu:fb72a08
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable G protein-coupled receptor activity. Acts upstream of or within endothelial cell-cell adhesion; negative regulation of hippo signaling; and regulation of vascular permeability. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain; eye; and tail bud. Orthologous to human ADGRL2 (adhesion G protein-coupled receptor L2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Camillo et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000203 | GPS motif |
| Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
| Domain | IPR000922 | D-galactoside/L-rhamnose binding SUEL lectin domain |
| Domain | IPR001879 | GPCR, family 2, extracellular hormone receptor domain |
| Domain | IPR003112 | Olfactomedin-like domain |
| Domain | IPR003334 | GPCR, family 2, latrophilin, C-terminal |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR032471 | AGRL2-4 , GAIN subdomain A |
| Domain | IPR057244 | GAIN, subdomain B |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR003924 | GPCR, family 2, latrophilin |
| Homologous_superfamily | IPR036445 | GPCR family 2, extracellular hormone receptor domain superfamily |
| Homologous_superfamily | IPR043159 | D-galactoside/L-rhamnose binding SUEL lectin domain superfamily |
| Homologous_superfamily | IPR046338 | GAIN domain superfamily |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adgrl2a-201
(1)
|
Ensembl | 6,618 nt | ||
| mRNA |
adgrl2a-203
(1)
|
Ensembl | 6,643 nt | ||
| mRNA |
adgrl2a-204
(1)
|
Ensembl | 6,823 nt | ||
| mRNA |
adgrl2a-205
(1)
|
Ensembl | 6,651 nt | ||
| mRNA |
adgrl2a-206
(1)
|
Ensembl | 6,374 nt | ||
| ncRNA |
adgrl2a-002
(1)
|
Ensembl | 574 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance