Gene
fth1a
- ID
- ZDB-GENE-000831-2
- Name
- ferritin, heavy polypeptide 1a
- Symbol
- fth1a Nomenclature History
- Previous Names
-
- fth1 (1)
- fb06g09
- hm:zeh1145
- wu:fb06g09
- wu:fq18c10
- zeh1145
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable ferric iron binding activity and ferrous iron binding activity. Predicted to be active in cytoplasm. Is expressed in blood; eye; liver; ovary; and testis. Human ortholog(s) of this gene implicated in hemochromatosis type 5 and neurodegeneration with brain iron accumulation. Orthologous to several human genes including FTH1 (ferritin heavy chain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55220 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hemochromatosis type 5 | Alliance | ?Hemochromatosis, type 5 | 615517 |
| Neurodegeneration with brain iron accumulation 9 | 620669 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ferritin | Ferritin, conserved site | Ferritin/DPS domain | Ferritin-like | Ferritin-like diiron domain | Ferritin-like superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q9DDT0 | InterPro | 177 |
Interactions and Pathways
No data available
Plasmids
No data available