ZFIN is now using GRCz12tu for Genomic Data
Gene
tbx15
- ID
- ZDB-GENE-020529-1
- Name
- T-box transcription factor 15
- Symbol
- tbx15 Nomenclature History
- Previous Names
-
- zgc:158205
- zgc:63576
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of DNA-templated transcription. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including cephalic musculature; head mesenchyme; mesenchyme pectoral fin; mesoderm pectoral fin bud; and pharyngeal arch 1. Orthologous to human TBX15 (T-box transcription factor 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147865 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cousin syndrome | 260660 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018186 | Transcription factor, T-box, conserved site |
| Domain | IPR046360 | T-box transcription factor, DNA-binding domain |
| Family | IPR001699 | T-box transcription factor |
| Homologous_superfamily | IPR008967 | p53-like transcription factor, DNA-binding domain superfamily |
| Homologous_superfamily | IPR036960 | T-box superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | p53-like transcription factor, DNA-binding domain superfamily | T-box superfamily | T-box transcription factor | T-box transcription factor, DNA-binding domain | Transcription factor, T-box, conserved site |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8QEJ0 | InterPro | 616 | |||||
| UniProtKB:A0A8M9QAK7 | InterPro | 510 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers