ZFIN is now using GRCz12tu for Genomic Data
Gene
ptgs2a
- ID
- ZDB-GENE-020530-2
- Name
- prostaglandin-endoperoxide synthase 2a
- Symbol
- ptgs2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables peroxidase activity. Acts upstream of or within several processes, including embryonic liver development; exocrine pancreas development; and pronephros development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and neuron projection. Is expressed in several structures, including cardiovascular system; digestive system; gonad; head; and trigeminal placode. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; arthritis (multiple); cardiovascular system disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 42 figures from 34 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like domain | Haem peroxidase, animal-type | Haem peroxidase domain superfamily, animal type | Haem peroxidase superfamily | Oxylipin biosynthesis and metabolism |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q8JH43 | InterPro | 601 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptgs2a-201
(1)
|
Ensembl | 2,135 nt | ||
| ncRNA |
ptgs2a-002
(1)
|
Ensembl | 673 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers