ZFIN is now using GRCz12tu for Genomic Data
Gene
pks1
- ID
- ZDB-GENE-030131-2238
- Name
- polyketide synthase 1
- Symbol
- pks1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable 3-oxoacyl-[acyl-carrier-protein] synthase activity. Acts upstream of or within otolith formation.
- Genome Resources
-
- Alliance (1)
- Gene:555390 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thiessen et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR018201 | Beta-ketoacyl synthase, active site |
| Domain | IPR009081 | Phosphopantetheine binding ACP domain |
| Domain | IPR014030 | Beta-ketoacyl synthase-like, N-terminal |
| Domain | IPR014031 | Beta-ketoacyl synthase, C-terminal |
| Domain | IPR014043 | Acyl transferase domain |
| Domain | IPR020841 | Polyketide synthase, beta-ketoacyl synthase domain |
| Domain | IPR032821 | Polyketide synthase, C-terminal extension |
| Domain | IPR049551 | Polyketide synthase, dehydratase domain, C-terminal |
| Family | IPR050444 | Polyketide synthase |
| Homologous_superfamily | IPR001227 | Acyl transferase domain superfamily |
| Homologous_superfamily | IPR011032 | GroES-like superfamily |
| Homologous_superfamily | IPR016035 | Acyl transferase/acyl hydrolase/lysophospholipase |
| Homologous_superfamily | IPR016036 | Malonyl-CoA ACP transacylase, ACP-binding |
| Homologous_superfamily | IPR016039 | Thiolase-like |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
| Homologous_superfamily | IPR036736 | ACP-like superfamily |
| Homologous_superfamily | IPR042104 | Polyketide synthase, dehydratase domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | ACP-like superfamily | Acyl transferase/acyl hydrolase/lysophospholipase | Acyl transferase domain | Acyl transferase domain superfamily | Beta-ketoacyl synthase, active site | Beta-ketoacyl synthase, C-terminal | Beta-ketoacyl synthase-like, N-terminal | GroES-like superfamily | Malonyl-CoA ACP transacylase, ACP-binding | NAD(P)-binding domain superfamily | Phosphopantetheine binding ACP domain | Polyketide synthase | Polyketide synthase, beta-ketoacyl synthase domain | Polyketide synthase, C-terminal extension | Polyketide synthase, dehydratase domain, C-terminal | Polyketide synthase, dehydratase domain superfamily | Thiolase-like |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6YY84 | InterPro | 2101 | |||||||||||||||||
| UniProtKB:A0A8N7T6L7 | InterPro | 2095 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance