Gene
tpm4b
- ID
- ZDB-GENE-030131-2964
- Name
- tropomyosin 4b
- Symbol
- tpm4b Nomenclature History
- Previous Names
-
- TPM4-2 alpha (1)
- wu:fc22f09
- zgc:63734
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization and muscle contraction. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in actin filament. Is expressed in cardiovascular system; cephalic musculature; epiphysis; and otic vesicle. Human ortholog(s) of this gene implicated in blood platelet disease. Orthologous to human TPM4 (tropomyosin 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63734 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bleeding disorder, platelet-type, 25 | 620486 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | DNA repair protein XRCC4-like, C-terminal | Tropomyosin |
|---|---|---|---|---|
| UniProtKB:A0A1L6UW65 | InterPro | 284 | ||
| UniProtKB:Q7SXW1 | InterPro | 248 | ||
| UniProtKB:A0A8M6Z082 | InterPro | 284 |
Interactions and Pathways
No data available
Plasmids
No data available