ZFIN is now using GRCz12tu for Genomic Data
Gene
sephs1
- ID
- ZDB-GENE-030131-3670
- Name
- selenophosphate synthetase 1
- Symbol
- sephs1 Nomenclature History
- Previous Names
-
- wu:fc49b09
- zgc:55304
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein heterodimerization activity; protein homodimerization activity; and selenide, water dikinase activity. Predicted to be involved in L-selenocysteine biosynthetic process and cell redox homeostasis. Predicted to be located in nuclear membrane and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human SEPHS1 (selenophosphate synthetase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ververi-Brady syndrome 2 | 621325 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR010918 | PurM-like, C-terminal domain |
| Domain | IPR016188 | PurM-like, N-terminal domain |
| Family | IPR004536 | Selenophosphate synthetase |
| Homologous_superfamily | IPR036676 | PurM-like, C-terminal domain superfamily |
| Homologous_superfamily | IPR036921 | PurM-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | PurM-like, C-terminal domain | PurM-like, C-terminal domain superfamily | PurM-like, N-terminal domain | PurM-like, N-terminal domain superfamily | Selenophosphate synthetase |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZW38 | InterPro | 392 | |||||
| UniProtKB:A0AB32TA65 | InterPro | 392 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sephs1-201
(1)
|
Ensembl | 2,113 nt | ||
| mRNA |
sephs1-202
(1)
|
Ensembl | 717 nt | ||
| mRNA |
sephs1-203
(1)
|
Ensembl | 1,182 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers