rpl27

ID

ZDB-GENE-030131-4343

Name

ribosomal protein L27

Symbol

rpl27 Nomenclature History

Previous Names

fc93a08
wu:fc93a08
zgc:56171 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to be a structural constituent of ribosome. Acts upstream of or within erythrocyte differentiation. Predicted to be located in cytoplasmic side of rough endoplasmic reticulum membrane. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in endodermal cell; intestine; liver; and pancreas. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56171 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Wang et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rpl27 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Diamond-Blackfan anemia 16	Alliance	?Diamond-Blackfan anemia 16	617408

Associated With rpl27 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018262	Large ribosomal subunit protein eL27, conserved site
Domain	IPR005824	KOW
Domain	IPR041991	Large ribosomal subunit protein eL27, KOW domain
Family	IPR001141	Large ribosomal subunit protein eL27
Homologous_superfamily	IPR008991	Translation protein SH3-like domain superfamily
Homologous_superfamily	IPR038655	Large ribosomal subunit protein eL27 superfamily