Gene
jam3b
- ID
- ZDB-GENE-030131-441
- Name
- junctional adhesion molecule 3b
- Symbol
- jam3b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable cell-cell adhesion mediator activity and integrin binding activity. Acts upstream of or within with a positive effect on myoblast fusion. Predicted to be located in bicellular tight junction and desmosome. Predicted to be part of protein complex involved in cell adhesion. Predicted to be active in cell-cell contact zone and plasma membrane. Is expressed in several structures, including cardiovascular system; hypodermis; musculature system; myoblast; and nervous system. Orthologous to human JAM3 (junctional adhesion molecule 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d123 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 18 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hemorrhagic destruction of the brain, subependymal calcification, and cataracts | 613730 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR042974 | Junctional adhesion molecule C |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Immunoglobulin V-set domain | Junctional adhesion molecule C |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A3KPA0 | InterPro | 302 |
Interactions and Pathways
No data available
Plasmids
No data available