ZFIN is now using GRCz12tu for Genomic Data
Gene
irx3b
- ID
- ZDB-GENE-030131-525
- Name
- iroquois homeobox 3b
- Symbol
- irx3b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within pronephric distal tubule development; pronephric duct morphogenesis; and pronephric nephron tubule epithelial cell differentiation. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; hindbrain neural keel; neural plate; neural rod; and pronephros. Orthologous to human IRX3 (iroquois homeobox 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Iroquois-class homeodomain protein | KN homeodomain |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NY58 | InterPro | 343 | |||||
| UniProtKB:A0A8M1PGB3 | InterPro | 343 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers