ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
mapkapk2a
- ID
- ZDB-GENE-030131-5532
- Name
- MAPK activated protein kinase 2a
- Symbol
- mapkapk2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables kinase activity. Acts upstream of or within epiboly involved in gastrulation with mouth forming second. Predicted to be active in cytoplasm and nucleus. Orthologous to human MAPKAPK2 (MAPK activated protein kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
- 
    
        
        
              
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- 
    
        
    
    
        
        - IMAGE:7138001 (1 image)
 
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Type | InterPro ID | Name | 
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site | 
| Binding_site | IPR017441 | Protein kinase, ATP binding site | 
| Domain | IPR000719 | Protein kinase domain | 
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily | 
| Homologous_superfamily | IPR027442 | MAP kinase activated protein kinase, C-terminal | 
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | MAP kinase activated protein kinase, C-terminal | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | 
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7T2F2 | InterPro | 382 | 
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis | 
|---|---|---|---|---|---|
| mRNA | mapkapk2a-201
                             (1) | Ensembl | 3,310 nt | 
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
        
    
    
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers
