ZFIN is now using GRCz12tu for Genomic Data
Gene
tdo2b
- ID
- ZDB-GENE-030131-6014
- Name
- tryptophan 2,3-dioxygenase b
- Symbol
- tdo2b Nomenclature History
- Previous Names
-
- tdo2l
- fi30d08
- wu:fi30d08
- zgc:63488 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable L-tryptophan 2,3-dioxygenase activity and heme binding activity. Predicted to be involved in L-tryptophan catabolic process and protein homotetramerization. Is expressed in gut and liver. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Orthologous to human TDO2 (tryptophan 2,3-dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63488 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Tryptophan 2,3-dioxygenase | Tryptophan/Indoleamine 2,3-dioxygenase-like |
|---|---|---|---|---|
| UniProtKB:Q7SY53 | InterPro | 407 | ||
| UniProtKB:A0A8M9QCY2 | InterPro | 403 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers