ZFIN is now using GRCz12tu for Genomic Data
Gene
hspa4b
- ID
- ZDB-GENE-030131-6018
- Name
- heat shock protein 4b
- Symbol
- hspa4b Nomenclature History
- Previous Names
-
- hspa4
- wu:fi30e11
- zgc:55743
- zgc:77413
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable adenyl-nucleotide exchange factor activity. Predicted to be involved in protein folding. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including gut; head; liver; neural rod; and pectoral fin bud. Human ortholog(s) of this gene implicated in Chagas disease. Orthologous to human HSPA4 (heat shock protein family A (Hsp70) member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018181 | Heat shock protein 70, conserved site |
| Domain | IPR042052 | HSPA4, nucleotide-binding domain |
| Family | IPR013126 | Heat shock protein 70 family |
| Homologous_superfamily | IPR029047 | Heat shock protein 70kD, peptide-binding domain superfamily |
| Homologous_superfamily | IPR029048 | Heat shock protein 70kD, C-terminal domain superfamily |
| Homologous_superfamily | IPR043129 | ATPase, nucleotide binding domain |
Domain Details Per Protein
| Protein | Additional Resources | Length | ATPase, nucleotide binding domain | Heat shock protein 70, conserved site | Heat shock protein 70 family | Heat shock protein 70kD, C-terminal domain superfamily | Heat shock protein 70kD, peptide-binding domain superfamily | HSPA4, nucleotide-binding domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZUM5 | InterPro | 840 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hspa4b-201
(1)
|
Ensembl | 3,010 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers