rbl1

ID

ZDB-GENE-030131-8179

Name

retinoblastoma-like 1 (p107)

Symbol

rbl1 Nomenclature History

Previous Names

fj58e06
wu:fj58e06

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and negative regulation of G1/S transition of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Predicted to be active in chromatin. Orthologous to human RBL1 (RB transcriptional corepressor like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rbl1 Human Ortholog

No data available

Associated With rbl1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002719	Retinoblastoma-associated protein, B-box
Domain	IPR002720	Retinoblastoma-associated protein, A-box
Domain	IPR013763	Cyclin-like domain
Domain	IPR015030	Retinoblastoma-associated protein, C-terminal
Domain	IPR024599	Retinoblastoma-associated protein, N-terminal
Family	IPR028309	Retinoblastoma protein family
Homologous_superfamily	IPR036915	Cyclin-like superfamily