Gene
tfg
- ID
- ZDB-GENE-030131-8410
- Name
- trafficking from ER to golgi regulator
- Symbol
- tfg Nomenclature History
- Previous Names
-
- wu:fb11c10
- zgc:55342
- zgc:77230
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Acts upstream of or within regulation of neuron projection development and swimming behavior. Predicted to be active in endoplasmic reticulum exit site. Is expressed in brain; eye; notochord; pectoral fin; and spinal cord. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 57. Orthologous to human TFG (trafficking from ER to golgi regulator).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55342 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Chen et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 2 | Alliance | Hereditary motor and sensory neuropathy, Okinawa type | 604484 |
| hereditary spastic paraplegia 57 | Alliance | ?Spastic paraplegia 57, autosomal recessive | 615658 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PB1 domain | PB1-like domain | Protein TFG | TFG, PB1 domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q6P0G5 | InterPro | 396 |
Interactions and Pathways
No data available
Plasmids
No data available