Gene
timeless
- ID
- ZDB-GENE-030131-8978
- Name
- timeless circadian clock
- Symbol
- timeless Nomenclature History
- Previous Names
-
- Tim (1)
- fa95g04
- fd23d07
- im:6903167
- wu:fa95g04
- wu:fd23d07
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity. Predicted to be involved in DNA repair; DNA replication checkpoint signaling; and replication fork arrest. Predicted to be located in nucleus. Predicted to be part of replication fork protection complex. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome 4 and alcohol use disorder. Orthologous to human TIMELESS (timeless circadian regulator).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6903167 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| advanced sleep phase syndrome 4 | Alliance | ?Advance sleep phase syndrome, familial, 4 | 620015 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Timeless | Timeless, C-terminal | Timeless, N-terminal |
|---|---|---|---|---|---|
| UniProtKB:E7FGL0 | InterPro | 1278 | |||
| UniProtKB:A0A2R8Q1Y3 | InterPro | 1239 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
timeless-201
(1)
|
Ensembl | 4,416 nt | ||
| mRNA |
timeless-202
(1)
|
Ensembl | 712 nt | ||
| mRNA |
timeless-203
(1)
|
Ensembl | 3,959 nt | ||
| mRNA |
timeless-204
(1)
|
Ensembl | 3,962 nt | ||
| mRNA |
timeless-205
(1)
|
Ensembl | 4,142 nt |
Interactions and Pathways
No data available
Plasmids
No data available