ZFIN is now using GRCz12tu for Genomic Data
Gene
mki67
- ID
- ZDB-GENE-030131-9771
- Name
- marker of proliferation Ki-67
- Symbol
- mki67 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in regulation of mitotic nuclear division. Predicted to be active in chromosome and nucleus. Is expressed in several structures, including blood; head; pectoral fin bud; pectoral fin musculature; and ventral mesoderm. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; colorectal cancer; endocrine gland cancer (multiple); graft-versus-host disease; and human immunodeficiency virus infectious disease. Orthologous to human MKI67 (marker of proliferation Ki-67).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb31 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Forkhead-associated (FHA) domain | KI67R | Protein phosphatase 1 binding domain | SMAD/FHA domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1NZY3 | InterPro | 2057 | ||||
| UniProtKB:A0A8M6Z3I0 | InterPro | 1886 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance