ZFIN is now using GRCz12tu for Genomic Data
Gene
quob
- ID
- ZDB-GENE-030131-9944
- Name
- quattro b
- Symbol
- quob Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within animal organ morphogenesis and mesoderm morphogenesis. Is expressed in several structures, including Kupffer's vesicle; anterior axial hypoblast; forerunner cell group; mesoderm; and nervous system. Orthologous to human KIAA1755 (KIAA1755).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb9 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000219 | Dbl homology domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR055251 | SOS1/NGEF-like, PH domain |
| Family | IPR052231 | Rho GEF and signaling-related domain-containing protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Dbl homology (DH) domain superfamily | Dbl homology domain | PH-like domain superfamily | Pleckstrin homology domain | Rho GEF and signaling-related domain-containing protein | SOS1/NGEF-like, PH domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6DN89 | InterPro | 1989 | ||||||
| UniProtKB:A0A8M1N225 | InterPro | 1987 | ||||||
| UniProtKB:A0AB32TQS0 | InterPro | 1988 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be the ortholog of human PLEKHG4 based on amino acid similarity. Subsequent analysis suggests it is the ortholog of human KIAA1755 and mouse D630003M21Rik based on amino acid similarity and conserved synteny.