ZFIN is now using GRCz12tu for Genomic Data

Gene

ncor2

ID

ZDB-GENE-030616-81

Name

nuclear receptor corepressor 2

Symbol

ncor2 Nomenclature History

Previous Names

gb:be017685
si:bz71m17.2
smrt (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable transcription corepressor activity. Acts upstream of or within hematopoietic stem cell differentiation; macrophage differentiation; and neutrophil differentiation. Predicted to be located in nuclear body. Predicted to be part of protein-containing complex. Predicted to be active in chromatin. Is expressed in several structures, including anterior axial hypoblast; cardiovascular system; central nervous system; eye; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human NCOR2 (nuclear receptor corepressor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

be017685 (18 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ncor2 Human Ortholog

No data available

Associated With ncor2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001005	SANT/Myb domain
Domain	IPR017884	SANT domain
Domain	IPR017930	Myb domain
Domain	IPR031557	N-CoR, GPS2-interacting domain
Family	IPR051571	Nuclear receptor corepressor
Homologous_superfamily	IPR009057	Homedomain-like superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PQX3	InterPro	2363
UniProtKB:E7FF48	InterPro	2315
UniProtKB:A0A8M3B547	InterPro	1757
UniProtKB:A0A8M3AVG1	InterPro	2379
UniProtKB:A0A8M6YZT2	InterPro	2353
UniProtKB:A0A8M6Z7M5	InterPro	2341
UniProtKB:A0A8M6Z833	InterPro	2369
UniProtKB:A0AC58G7L1	InterPro	2379
UniProtKB:A0AC58G7L3	InterPro	2379
UniProtKB:A0AC58G7L7	InterPro	2325
UniProtKB:A0AC58G7L9	InterPro	2379
UniProtKB:A0AC58G7M0	InterPro	2379
UniProtKB:A0AC58G7M1	InterPro	2325
UniProtKB:A0AC58G7M2	InterPro	2331
UniProtKB:A0AC58G7M3	InterPro	2363
UniProtKB:A0AC58G7M4	InterPro	2331
UniProtKB:A0AC58G7M5	InterPro	2325
UniProtKB:A0AC58G7M6	InterPro	2341
UniProtKB:A0AC58G7M7	InterPro	2353
UniProtKB:A0AC58G7M8	InterPro	1757
UniProtKB:A0AC58G7M9	InterPro	2315
UniProtKB:A0AC58G7N0	InterPro	2331
UniProtKB:A0AC58G7N1	InterPro	1747
UniProtKB:A0AC58G7N2	InterPro	1693
UniProtKB:A0AC58G7N3	InterPro	1757
UniProtKB:A0AC58G7N4	InterPro	1741
UniProtKB:A0AC58G7N5	InterPro	1741
UniProtKB:A0AC58G7N6	InterPro	1703
UniProtKB:A0AC58G7N7	InterPro	1703
UniProtKB:A0AC58G7N8	InterPro	1709
UniProtKB:A0AC58G7N9	InterPro	1693
UniProtKB:A0AC58G7P1	InterPro	1731
UniProtKB:A0AC58G7P5	InterPro	1719
UniProtKB:A0AC58G7P6	InterPro	1719
UniProtKB:A0AC58G7P7	InterPro	1709

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ncor2-201 (1) Ensembl	Ensembl	6,325 nt	Select Tool ZFIN BLAST
mRNA	ncor2-202 (1) Ensembl	Ensembl	9,984 nt	Select Tool ZFIN BLAST
mRNA	ncor2-204 (1) Ensembl	Ensembl	6,295 nt	Select Tool ZFIN BLAST
ncRNA	ncor2-003 (1) Ensembl	Ensembl	539 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations