ZFIN is now using GRCz12tu for Genomic Data
Gene
hspa9
- ID
- ZDB-GENE-030828-12
- Name
- heat shock protein 9
- Symbol
- hspa9 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Acts upstream of or within fin regeneration and hemopoiesis. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in several structures, including digestive system; eye; fin; midbrain; and segmental plate. Human ortholog(s) of this gene implicated in Parkinson's disease and autosomal dominant sideroblastic anemia 4. Orthologous to human HSPA9 (heat shock protein family A (Hsp70) member 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb740 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant sideroblastic anemia 4 | Alliance | Anemia, sideroblastic, 4 | 182170 |
| Even-plus syndrome | 616854 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018181 | Heat shock protein 70, conserved site |
| Family | IPR012725 | Chaperone DnaK |
| Family | IPR013126 | Heat shock protein 70 family |
| Homologous_superfamily | IPR029047 | Heat shock protein 70kD, peptide-binding domain superfamily |
| Homologous_superfamily | IPR029048 | Heat shock protein 70kD, C-terminal domain superfamily |
| Homologous_superfamily | IPR043129 | ATPase, nucleotide binding domain |
Domain Details Per Protein
| Protein | Additional Resources | Length | ATPase, nucleotide binding domain | Chaperone DnaK | Heat shock protein 70, conserved site | Heat shock protein 70 family | Heat shock protein 70kD, C-terminal domain superfamily | Heat shock protein 70kD, peptide-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5XJ12 | InterPro | 682 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers