fstb

ID

ZDB-GENE-031118-139

Name

follistatin b

Symbol

fstb Nomenclature History

Previous Names

fst2 (2)
fstl
hm:zeh1606
zeh1606
zgc:171342

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable activin binding activity. Predicted to be involved in cell differentiation; negative regulation of activin receptor signaling pathway; and regulation of BMP signaling pathway. Predicted to be active in extracellular space. Is expressed in several structures, including brain; heart; integument; pharyngeal arch 3-7 skeleton; and somite. Human ortholog(s) of this gene implicated in polycystic ovary syndrome. Orthologous to human FST (follistatin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fstb Human Ortholog

No data available

Associated With fstb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002350	Kazal domain
Domain	IPR003645	Follistatin-like, N-terminal
Domain	IPR015369	Follistatin/Osteonectin EGF domain
Domain	IPR017878	TB domain
Homologous_superfamily	IPR036058	Kazal domain superfamily
Homologous_superfamily	IPR036773	TGF-beta binding (TB) domain superfamily