Gene
scap
- ID
- ZDB-GENE-040107-41
- Name
- SREBF chaperone
- Symbol
- scap Nomenclature History
- Previous Names
-
- si:dkey-201i6.4
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable sterol binding activity. Acts upstream of or within lipid metabolic process and lipid storage. Predicted to be located in ER to Golgi transport vesicle membrane; Golgi membrane; and endoplasmic reticulum. Predicted to be part of SREBP-SCAP complex. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SCAP (SREBF chaperone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR000731 | Sterol-sensing domain |
| Domain | IPR053958 | HMGCR/SNAP/NPC1-like, sterol-sensing domain |
| Family | IPR030225 | Sterol regulatory element-binding protein cleavage-activating protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | HMGCR/SNAP/NPC1-like, sterol-sensing domain | Sterol regulatory element-binding protein cleavage-activating protein | Sterol-sensing domain | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B4M5 | InterPro | 1294 | |||||||
| UniProtKB:E9QEH6 | InterPro | 1245 |
Interactions and Pathways
No data available
Plasmids
No data available