ZFIN is now using GRCz12tu for Genomic Data
Gene
cyp2p10
- ID
- ZDB-GENE-040120-1
- Name
- cytochrome P450, family 2, subfamily P, polypeptide 10
- Symbol
- cyp2p10 Nomenclature History
- Previous Names
-
- cyp2j21
- cyp2j2a (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including nervous system; neural plate; neural rod; neural tube; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypertension (multiple); myocardial infarction; and renal fibrosis. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56663 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017972 | Cytochrome P450, conserved site |
| Family | IPR001128 | Cytochrome P450 |
| Family | IPR002401 | Cytochrome P450, E-class, group I |
| Family | IPR008069 | Cytochrome P450, E-class, group I, CYP2D-like |
| Family | IPR050182 | Cytochrome P450 family 2 |
| Homologous_superfamily | IPR036396 | Cytochrome P450 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450, E-class, group I, CYP2D-like | Cytochrome P450 family 2 | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZU60 | InterPro | 497 | ||||||
| UniProtKB:A0A8M2B7E8 | InterPro | 282 | ||||||
| UniProtKB:A0A8M3B1F6 | InterPro | 338 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp2p10-201
(1)
|
Ensembl | 1,715 nt | ||
| mRNA |
cyp2p10-202
(1)
|
Ensembl | 1,646 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers