ZFIN is now using GRCz12tu for Genomic Data
Gene
rab5ab
- ID
- ZDB-GENE-040122-3
- Name
- RAB5A, member RAS oncogene family, b
- Symbol
- rab5ab Nomenclature History
- Previous Names
-
- rab5al
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTPase activity. Acts upstream of or within several processes, including Spemann organizer formation; epiboly involved in gastrulation with mouth forming second; and nodal signaling pathway. Predicted to be located in early endosome membrane. Predicted to be active in axon; cytoplasmic vesicle; and plasma membrane. Orthologous to human RAB5A (RAB5A, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138917 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Kenyon et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|
| UniProtKB:Q7ZUG4 | InterPro | 216 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rab5ab-201
(1)
|
Ensembl | 1,279 nt | ||
| mRNA |
rab5ab-202
(1)
|
Ensembl | 823 nt |
Interactions and Pathways
No data available
Plasmids
- Genome Browsers