ZFIN is now using GRCz12tu for Genomic Data
Gene
gpr143
- ID
- ZDB-GENE-040426-1476
- Name
- G protein-coupled receptor 143
- Symbol
- gpr143 Nomenclature History
- Previous Names
-
- zgc:65915
- zgc:77322 (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable L-DOPA receptor activity; carboxylic acid binding activity; and dopamine binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and melanosome organization. Predicted to be active in melanosome membrane and plasma membrane. Is expressed in neural crest; pigment cell; retina; and retinal pigmented epithelium. Human ortholog(s) of this gene implicated in congenital nystagmus 6 and ocular albinism 1. Orthologous to human GPR143 (G protein-coupled receptor 143).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65915 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Burgoyne et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital nystagmus 6 | Alliance | Nystagmus 6, congenital, X-linked | 300814 |
| ocular albinism 1 | Alliance | Ocular albinism, type I, Nettleship-Falls type | 300500 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M3AWB8 | InterPro | 412 |
| UniProtKB:A0AC36K4V6 | InterPro | 412 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gpr143-201
(1)
|
Ensembl | 1,239 nt | ||
| mRNA |
gpr143-202
(1)
|
Ensembl | 864 nt | ||
| mRNA |
gpr143-203
(1)
|
Ensembl | 646 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers