ZFIN is now using GRCz12tu for Genomic Data
Gene
bcl6aa
- ID
- ZDB-GENE-040426-1696
- Name
- BCL6A transcription repressor a
- Symbol
- bcl6aa Nomenclature History
- Previous Names
-
- bcl6
- bcl6a
- zgc:73162
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within several processes, including negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; regulation of leukocyte differentiation; and regulation of macrophage migration. Predicted to be active in nucleus. Is expressed in lateral mesoderm; myotome; nervous system; and thymus. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73162 (8 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | BTB/POZ domain | SKP1/BTB/POZ domain superfamily | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|
| UniProtKB:F1R5N6 | InterPro | 718 | ||||
| UniProtKB:A0A8M9PZK1 | InterPro | 748 | ||||
| UniProtKB:A0A8M9Q608 | InterPro | 704 | ||||
| UniProtKB:Q6PC08 | InterPro | 704 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers