Gene
skp1
- ID
- ZDB-GENE-040426-1707
- Name
- S-phase kinase-associated protein 1
- Symbol
- skp1 Nomenclature History
- Previous Names
-
- skp1a
- zgc:73186
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within phosphorylation. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human SKP1 (S-phase kinase associated protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73186 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR016072 | SKP1 component, dimerisation |
| Domain | IPR016073 | SKP1 component, POZ domain |
| Family | IPR001232 | S-phase kinase-associated protein 1-like |
| Family | IPR016897 | S-phase kinase-associated protein 1 |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR036296 | SKP1-like, dimerisation domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | SKP1/BTB/POZ domain superfamily | SKP1 component, dimerisation | SKP1 component, POZ domain | SKP1-like, dimerisation domain superfamily | S-phase kinase-associated protein 1 | S-phase kinase-associated protein 1-like |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6PBY8 | InterPro | 163 |
Interactions and Pathways
No data available
Plasmids
No data available