Gene
hnrnpc
- ID
- ZDB-GENE-040426-2043
- Name
- heterogeneous nuclear ribonucleoprotein C
- Symbol
- hnrnpc Nomenclature History
- Previous Names
-
- fb57h12
- fi16b11
- wu:fb57h12 (1)
- wu:fi16b11
- zgc:55701
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Enables mRNA 3'-UTR binding activity. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 74. Orthologous to human HNRNPC (heterogeneous nuclear ribonucleoprotein C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55701 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 74 | Alliance | Intellectual developmental disorder, autosomal dominant 74 | 620688 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Family | IPR017347 | Heterogeneous nuclear ribonucleoprotein C |
| Family | IPR051186 | RRM HNRPC family, RALY subfamily |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Heterogeneous nuclear ribonucleoprotein C | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | RRM HNRPC family, RALY subfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q728 | InterPro | 393 | |||||
| UniProtKB:Q803J4 | InterPro | 313 | |||||
| UniProtKB:A0A8M6Z8V1 | InterPro | 312 | |||||
| UniProtKB:A0A8M9PUR6 | InterPro | 392 | |||||
| UniProtKB:A0AB32TXW0 | InterPro | 484 | |||||
| UniProtKB:A0AB32U0G3 | InterPro | 404 | |||||
| UniProtKB:A0AB32U1U2 | InterPro | 483 | |||||
| UniProtKB:A0AB32U1W5 | InterPro | 403 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hnrnpc-201
(1)
|
Ensembl | 1,726 nt |
Interactions and Pathways
No data available
Plasmids
No data available