ZFIN is now using GRCz12tu for Genomic Data
Gene
pfkfb3
- ID
- ZDB-GENE-040426-2724
- Name
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
- Symbol
- pfkfb3 Nomenclature History
- Previous Names
-
- zgc:73257
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to act upstream of or within fructose metabolic process and phosphorylation. Predicted to be active in cytosol. Is expressed in Purkinje cell. Orthologous to human PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR001345 | Phosphoglycerate/bisphosphoglycerate mutase, active site |
| Domain | IPR013079 | 6-phosphofructo-2-kinase |
| Family | IPR003094 | Fructose-2,6-bisphosphatase |
| Family | IPR013078 | Histidine phosphatase superfamily, clade-1 |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR029033 | Histidine phosphatase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | 6-phosphofructo-2-kinase | Fructose-2,6-bisphosphatase | Histidine phosphatase superfamily | Histidine phosphatase superfamily, clade-1 | Phosphoglycerate/bisphosphoglycerate mutase, active site | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IBD1 | InterPro | 527 | ||||||
| UniProtKB:A0A8M2BC55 | InterPro | 519 | ||||||
| UniProtKB:A0A8M9PH83 | InterPro | 296 | ||||||
| UniProtKB:Q6P951 | InterPro | 536 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pfkfb3-201
(1)
|
Ensembl | 3,328 nt | ||
| mRNA |
pfkfb3-205
(1)
|
Ensembl | 3,525 nt | ||
| ncRNA |
pfkfb3-002
(1)
|
Ensembl | 789 nt | ||
| ncRNA |
pfkfb3-003
(1)
|
Ensembl | 724 nt | ||
| ncRNA |
pfkfb3-004
(1)
|
Ensembl | 464 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers