Gene
znf488
- ID
- ZDB-GENE-040426-2747
- Name
- zinc finger protein 488
- Symbol
- znf488 Nomenclature History
- Previous Names
-
- prdm8 (1)
- wu:fd12b11
- zgc:63680
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity and methyltransferase activity. Acts upstream of or within spinal cord motor neuron cell fate specification. Predicted to be active in nucleus. Is expressed in nervous system; neural plate; and neural tube. Orthologous to human ZNF488 (zinc finger protein 488).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7137167 (19 images)
- IMAGE:7158686 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Scott et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001214 | SET domain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Domain | IPR044402 | PRDM8-like, PR/SET domain |
| Family | IPR052296 | Transcriptional Repressor and Histone Methyltransferase |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | PRDM8-like, PR/SET domain | SET domain | SET domain superfamily | Transcriptional Repressor and Histone Methyltransferase | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:B8A5Y1 | InterPro | 502 | ||||||
| UniProtKB:Q7SXY1 | InterPro | 502 | ||||||
| UniProtKB:A0AAB0H375 | InterPro | 502 |
Interactions and Pathways
No data available
Plasmids
No data available