ZFIN is now using GRCz12tu for Genomic Data
Gene
pgd
- ID
- ZDB-GENE-040426-2807
- Name
- phosphogluconate dehydrogenase
- Symbol
- pgd Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable NADP binding activity and phosphogluconate dehydrogenase (decarboxylating) activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Predicted to act upstream of or within D-gluconate metabolic process and pentose-phosphate shunt. Predicted to be active in cytosol. Is expressed in several structures, including axis; chordo neural hinge; digestive system; sensory system; and solid lens vesicle. Orthologous to human PGD (phosphogluconate dehydrogenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55585 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Facchinello et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR006184 | 6-phosphogluconate-binding site |
| Domain | IPR006114 | 6-phosphogluconate dehydrogenase, C-terminal |
| Domain | IPR006115 | 6-phosphogluconate dehydrogenase, NADP-binding |
| Family | IPR006113 | 6-phosphogluconate dehydrogenase, decarboxylating |
| Family | IPR006183 | 6-phosphogluconate dehydrogenase |
| Homologous_superfamily | IPR008927 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily |
| Homologous_superfamily | IPR013328 | 6-phosphogluconate dehydrogenase, domain 2 |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | 6-phosphogluconate-binding site | 6-phosphogluconate dehydrogenase | 6-phosphogluconate dehydrogenase, C-terminal | 6-phosphogluconate dehydrogenase, decarboxylating | 6-phosphogluconate dehydrogenase, domain 2 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | 6-phosphogluconate dehydrogenase, NADP-binding | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1Q883 | InterPro | 511 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers