ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
edem1
- ID
 - ZDB-GENE-040426-808
 - Name
 - ER degradation enhancer, mannosidase alpha-like 1
 - Symbol
 - edem1 Nomenclature History
 - Previous Names
 - 
    
        
    
    
        
        
- zgc:55816 (1)
 
 - Type
 - protein_coding_gene
 - Location
 - Chr: 6 Mapping Details/Browsers
 - Genome Assembly
 - GRCz12tu
 - Annotation Status
 - Current
 - Description
 - Predicted to enable calcium ion binding activity and mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to act upstream of or within carbohydrate metabolic process; endoplasmic reticulum mannose trimming; and mannose trimming involved in glycoprotein ERAD pathway. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in anterior axial hypoblast; hatching gland; head; liver; and polster. Orthologous to human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1).
 - Genome Resources
 - Note
 - None
 - Comparative Information
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- All Expression Data
 - 19 figures from 14 publications
 - Cross-Species Comparison
 - High Throughput Data
 - Thisse Expression Data
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- MGC:55816 (4 images)
 
 
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    - All Phenotype Data
 - No data available
 - Cross-Species Comparison
 - Alliance
 
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    
    
    
            
        
    
    
    
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | ER degradation-enhancing alpha-mannosidase-like protein 1/2/3 | Glycoside hydrolase family 47 | Seven-hairpin glycosidases | Six-hairpin glycosidase-like superfamily | 
|---|---|---|---|---|---|---|
| UniProtKB:E9QJF1 | InterPro | 628 | 
- Genome Browsers
 
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers