Gene
rorab
- ID
- ZDB-GENE-040426-855
- Name
- RAR-related orphan receptor A, paralog b
- Symbol
- rorab Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including alar plate midbrain region; brain; immature eye; optic primordium; and visual system. Orthologous to human RORA (RAR related orphan receptor A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 35 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu270 (9 images)
- bc051158 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with or without epilepsy or cerebellar ataxia | 618060 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Domain | IPR044101 | Retinoid-related orphan receptors, DNA-binding domain |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR003079 | Nuclear receptor ROR |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nuclear hormone receptor | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Nuclear receptor ROR | Retinoid-related orphan receptors, DNA-binding domain | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QBZ9 | InterPro | 516 | |||||||
| UniProtKB:F1QJF4 | InterPro | 474 | |||||||
| UniProtKB:A0A8M6YZZ4 | InterPro | 545 | |||||||
| UniProtKB:A0A1D5NSP3 | InterPro | 526 |
Interactions and Pathways
No data available
Plasmids
No data available