ZFIN is now using GRCz12tu for Genomic Data
Gene
cnr2
- ID
- ZDB-GENE-040702-7
- Name
- cannabinoid receptor 2
- Symbol
- cnr2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cannabinoid receptor activity. Acts upstream of or within several processes, including L-methionine biosynthetic process; hematopoietic stem cell differentiation; and hematopoietic stem cell migration to bone marrow. Predicted to be located in membrane and neuron projection. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including digestive system; gill; heart; hematopoietic system; and nervous system. Used to study anxiety disorder. Orthologous to human CNR2 (cannabinoid receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| anxiety disorder | cnr2upr1/upr1 (NHGRI-1) | standard conditions | Acevedo-Canabal et al., 2019 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cannabinoid receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
| UniProtKB:Q20HN0 | InterPro | 383 | |||
| UniProtKB:A0AB32T6I4 | InterPro | 383 | |||
| UniProtKB:A0AC58HHE1 | InterPro | 383 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers