ZFIN is now using GRCz12tu for Genomic Data
Gene
tnfsf10
- ID
- ZDB-GENE-040718-335
- Name
- TNF superfamily member 10
- Symbol
- tnfsf10 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cytokine activity. Predicted to be involved in cell surface receptor signaling pathway; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in extracellular region. Is expressed in anterior lateral line neuromast; brain; ovary; posterior lateral line neuromast; and testis. Human ortholog(s) of this gene implicated in arteriosclerosis and small cell carcinoma. Orthologous to human TNFSF10 (TNF superfamily member 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Serbanovic-Canic et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Tumour necrosis factor, conserved site | Tumour necrosis factor domain | Tumour necrosis factor ligand 10/11 | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q6DHG9 | InterPro | 299 | ||||
| UniProtKB:A0A2R8QAD8 | InterPro | 286 | ||||
| UniProtKB:A0AC58IQ37 | InterPro | 286 | ||||
| UniProtKB:A0AC58IQ41 | InterPro | 299 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnfsf10-201
(1)
|
Ensembl | 1,879 nt | ||
| mRNA |
tnfsf10-202
(1)
|
Ensembl | 1,836 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers