ZFIN is now using GRCz12tu for Genomic Data
Gene
sart3
- ID
- ZDB-GENE-040724-10
- Name
- spliceosome associated factor 3, U4/U6 recycling protein
- Symbol
- sart3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable U6 snRNA binding activity and histone binding activity. Involved in spliceosomal snRNP assembly. Acts upstream of or within several processes, including exocrine pancreas development; hematopoietic stem cell homeostasis; and spliceosomal complex assembly. Predicted to be located in Cajal body. Predicted to be part of ASAP complex; U4/U6 snRNP; and U6atac snRNP. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human SART3 (spliceosome associated factor 3, U4/U6 recycling protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151848 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR008847 | Suppressor of forked |
| Domain | IPR034217 | SART3, RNA recognition motif 1 |
| Domain | IPR034218 | SART3, RNA recognition motif 2 |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
| Repeat | IPR003107 | HAT (Half-A-TPR) repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | HAT (Half-A-TPR) repeat | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | SART3, RNA recognition motif 1 | SART3, RNA recognition motif 2 | Suppressor of forked | Tetratricopeptide-like helical domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6ZM52 | InterPro | 951 | ||||||||
| UniProtKB:B3DJT0 | InterPro | 951 | ||||||||
| UniProtKB:A0AB32TR34 | InterPro | 951 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers