Gene

uevld

ID

ZDB-GENE-040801-138

Name

UEV and lactate/malate dehyrogenase domains

Symbol

uevld Nomenclature History

Previous Names

wu:fb14b11
zgc:100959

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to enable ubiquitin binding activity. Predicted to be involved in endosome to lysosome transport. Predicted to act upstream of or within carboxylic acid metabolic process and protein transport. Predicted to be part of ESCRT I complex. Orthologous to human UEVLD (UEV and lactate/malate dehyrogenase domains).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Lam et al., 2011

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With uevld Human Ortholog

No data available

Associated With uevld Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001236	Lactate/malate dehydrogenase, N-terminal
Domain	IPR008883	Ubiquitin E2 variant, N-terminal
Domain	IPR022383	Lactate/malate dehydrogenase, C-terminal
Family	IPR001557	L-lactate/malate dehydrogenase
Homologous_superfamily	IPR015955	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Homologous_superfamily	IPR016135	Ubiquitin-conjugating enzyme/RWD-like
Homologous_superfamily	IPR036291	NAD(P)-binding domain superfamily