pdia8

ID

ZDB-GENE-040801-20

Name

protein disulfide isomerase family A, member 8

Symbol

pdia8 Nomenclature History

Previous Names

erp57l2 (1)
zgc:100906

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable protein disulfide isomerase activity. Predicted to be involved in protein folding and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum lumen and melanosome. Predicted to be active in cell surface and endoplasmic reticulum. Is expressed in nervous system; neural tube; and trigeminal placode.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7144044 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pdia8 Human Ortholog

No data available

Associated With pdia8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017937	Thioredoxin, conserved site
Domain	IPR005788	Protein disulfide-isomerase, thioredoxin-like domain
Domain	IPR013766	Thioredoxin domain
Domain	IPR041868	Protein disulfide-isomerase A3, first redox inactive TRX-like domain b
Family	IPR005792	Protein disulphide isomerase
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily