ZFIN is now using GRCz12tu for Genomic Data

Gene

rbfox1

ID

ZDB-GENE-040927-11

Name

RNA binding fox-1 homolog 1

Symbol

rbfox1 Nomenclature History

Previous Names

a2bp1
zgc:103635 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable mRNA binding activity. Acts upstream of or within several processes, including left ventricular cardiac muscle tissue morphogenesis; regulation of alternative mRNA splicing, via spliceosome; and swimming behavior. Predicted to be active in cytoplasm and nucleus. Is expressed in digestive system; heart; nervous system; neural keel; and skeletal muscle. Human ortholog(s) of this gene implicated in alcohol use disorder. Orthologous to human RBFOX1 (RNA binding fox-1 homolog 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:103635 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rbfox1 Human Ortholog

No data available

Associated With rbfox1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR025670	Fox-1 C-terminal domain
Domain	IPR034237	FOX1, RNA recognition motif
Family	IPR017325	RNA binding protein fox-1 homolog 1-3
Family	IPR047131	RNA binding protein fox-1 homolog 1-like
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M6YYC7	InterPro	377
UniProtKB:A0A8M9PY79	InterPro	368
UniProtKB:A0A8M9PMK8	InterPro	362
UniProtKB:A0A8M9PY74	InterPro	391
UniProtKB:A0A8M6YWH6	InterPro	355
UniProtKB:A0A8M9P6C2	InterPro	364
UniProtKB:A0A8M6YWH2	InterPro	395
UniProtKB:A0A8M9PUS3	InterPro	388
UniProtKB:A0A8M9PY70	InterPro	394
UniProtKB:A0A8M9P6B9	InterPro	377
UniProtKB:A0A8M9PUS8	InterPro	364
UniProtKB:Q642J5	InterPro	373
UniProtKB:A0A8M6YVW0	InterPro	372
UniProtKB:A0A8M6Z4X9	InterPro	375
UniProtKB:A0A8M9PY89	InterPro	337
UniProtKB:A0AB32TAC1	InterPro	368
UniProtKB:A0AB32TBW4	InterPro	399
UniProtKB:A0AB32TBY0	InterPro	364
UniProtKB:A0AB32TCU5	InterPro	395
UniProtKB:A0AB32TD72	InterPro	368
UniProtKB:A0AB32TDQ2	InterPro	341
UniProtKB:A0AB32TE58	InterPro	392
UniProtKB:A0AB32TFM4	InterPro	381
UniProtKB:A0AB32TFU6	InterPro	366
UniProtKB:A0AB32THB3	InterPro	372
UniProtKB:A0AC58INH0	InterPro	391
UniProtKB:A0AC58INI1	InterPro	388
UniProtKB:A0AC58INL0	InterPro	371
UniProtKB:A0AC58INL3	InterPro	368
UniProtKB:A0AC58INM5	InterPro	368
UniProtKB:A0AC58INN3	InterPro	370
UniProtKB:A0AC58INN6	InterPro	368
UniProtKB:A0AC58INQ3	InterPro	357
UniProtKB:A0AC58INQ8	InterPro	351
UniProtKB:A0AC58INR2	InterPro	365
UniProtKB:A0AC58INR9	InterPro	345
UniProtKB:A0AC58INS1	InterPro	348
UniProtKB:A0AC58INS2	InterPro	348
UniProtKB:A0AC58INT0	InterPro	350
UniProtKB:A0AC58INU9	InterPro	346
UniProtKB:A0AC58INV0	InterPro	342
UniProtKB:A0AC58INV8	InterPro	340
UniProtKB:A0AC58INW4	InterPro	344
UniProtKB:A0AC58INW6	InterPro	344
UniProtKB:A0AC58INW8	InterPro	342
UniProtKB:A0AC58INX4	InterPro	324
UniProtKB:A0AC58INX6	InterPro	337
UniProtKB:A0AC58INY0	InterPro	322
UniProtKB:A0AC58INY1	InterPro	339
UniProtKB:A0AC58INY4	InterPro	337
UniProtKB:A0AC58INZ8	InterPro	328
UniProtKB:A0AC58IP02	InterPro	320
UniProtKB:A0AC58IP06	InterPro	328
UniProtKB:A0AC58IP10	InterPro	314
UniProtKB:A0AC58IP15	InterPro	317
UniProtKB:A0AC58IP16	InterPro	317
UniProtKB:A0AC58IP21	InterPro	319
UniProtKB:A0AC58IP34	InterPro	288
UniProtKB:A0AC58IP37	InterPro	283
UniProtKB:A0AC58IP44	InterPro	313
UniProtKB:A0AC58IP48	InterPro	319
UniProtKB:A0AC58IP49	InterPro	314
UniProtKB:A0AC58IP69	InterPro	297
UniProtKB:A0AC58IP70	InterPro	297

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rbfox1-202 (1) Ensembl	Ensembl	3,190 nt	Select Tool ZFIN BLAST
mRNA	rbfox1-203 (1) Ensembl	Ensembl	944 nt	Select Tool ZFIN BLAST
mRNA	rbfox1-204 (1) Ensembl	Ensembl	759 nt	Select Tool ZFIN BLAST
mRNA	rbfox1-205 (1) Ensembl	Ensembl	774 nt	Select Tool ZFIN BLAST
mRNA	rbfox1-206 (1) Ensembl	Ensembl	865 nt	Select Tool ZFIN BLAST
mRNA	rbfox1-207 (1) Ensembl	Ensembl	4,963 nt	Select Tool ZFIN BLAST
mRNA	rbfox1-208 (1) Ensembl	Ensembl	4,987 nt	Select Tool ZFIN BLAST
ncRNA	rbfox1-002 (1) Ensembl	Ensembl	662 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations