ZFIN is now using GRCz12tu for Genomic Data
Gene
hsd17b2
- ID
- ZDB-GENE-040928-1
- Name
- hydroxysteroid (17-beta) dehydrogenase 2
- Symbol
- hsd17b2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable steroid dehydrogenase activity. Predicted to be involved in androgen biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in brain; heart; integument; pleuroperitoneal region; and trunk musculature. Orthologous to human HSD17B2 (hydroxysteroid 17-beta dehydrogenase 2).
- Genome Resources
- Note
-
Mindnich et al. Steroid Biochem. Mol. Biol. 103(1): 35-43 suggest this may be a pseudogene.
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | NAD(P)-binding domain superfamily | Short-chain dehydrogenase/reductase, conserved site | Short-chain dehydrogenase/reductase SDR |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BAC5 | InterPro | 381 | |||
| UniProtKB:Q1PLL0 | InterPro | 358 | |||
| UniProtKB:A0AB32TKP2 | InterPro | 306 | |||
| UniProtKB:A0AC58IV55 | InterPro | 270 | |||
| UniProtKB:A0AC58IV56 | InterPro | 193 | |||
| UniProtKB:A0AC58IV60 | InterPro | 345 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hsd17b2-201
(1)
|
Ensembl | 1,144 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers