ZFIN is now using GRCz12tu for Genomic Data
Gene
ryr3
- ID
- ZDB-GENE-041001-165
- Name
- ryanodine receptor 3
- Symbol
- ryr3 Nomenclature History
- Previous Names
-
- ryrg (1)
- si:ch211-189g6.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ryanodine-sensitive calcium-release channel activity. Involved in nervous system development and skeletal muscle fiber development. Predicted to be located in sarcoplasmic reticulum membrane. Predicted to be active in sarcoplasmic reticulum. Is expressed in Kupffer's vesicle; brain; musculature system; neurons; and somite. Human ortholog(s) of this gene implicated in congenital myopathy 20 and hepatocellular carcinoma. Orthologous to human RYR3 (ryanodine receptor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1589 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital myopathy 20 | Alliance | Congenital myopathy 20 | 620310 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000699 | RIH domain |
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR002048 | EF-hand domain |
| Domain | IPR003032 | Ryanodine receptor Ryr |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR005821 | Ion transport domain |
| Domain | IPR009460 | Ryanodine Receptor TM 4-6 |
| Domain | IPR013662 | RyR/IP3R Homology associated domain |
| Domain | IPR014821 | Inositol 1,4,5-trisphosphate/ryanodine receptor |
| Domain | IPR016093 | MIR motif |
| Domain | IPR035761 | Ryanodine receptor, SPRY domain 1 |
| Domain | IPR035762 | Ryanodine receptor, SPRY domain 3 |
| Domain | IPR035764 | Ryanodine receptor, SPRY domain 2 |
| Domain | IPR048581 | Ryanodine receptor, junctional solenoid domain |
| Family | IPR013333 | Ryanodine receptor |
| Family | IPR015925 | Ryanodine/Inositol 1,4,5-trisphosphate receptor |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR035910 | RyR/IP3 receptor binding core, RIH domain superfamily |
| Homologous_superfamily | IPR036300 | Mir domain superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | Concanavalin A-like lectin/glucanase domain superfamily | EF-hand domain | EF-hand domain pair | Inositol 1,4,5-trisphosphate/ryanodine receptor | Ion transport domain | Mir domain superfamily | MIR motif | RIH domain | Ryanodine/Inositol 1,4,5-trisphosphate receptor | Ryanodine receptor | Ryanodine receptor, junctional solenoid domain | Ryanodine receptor Ryr | Ryanodine receptor, SPRY domain 1 | Ryanodine receptor, SPRY domain 2 | Ryanodine receptor, SPRY domain 3 | Ryanodine Receptor TM 4-6 | RyR/IP3 receptor binding core, RIH domain superfamily | RyR/IP3R Homology associated domain | SPRY domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3ATC3 | InterPro | 4856 | |||||||||||||||||||||
| UniProtKB:A0A8M3AWD0 | InterPro | 4857 | |||||||||||||||||||||
| UniProtKB:A0A8M3ALN1 | InterPro | 4863 | |||||||||||||||||||||
| UniProtKB:A0AB32TAU4 | InterPro | 4861 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers