ZFIN is now using GRCz12tu for Genomic Data
Gene
trdn
- ID
- ZDB-GENE-041014-193
- Name
- triadin
- Symbol
- trdn Nomenclature History
- Previous Names
-
- si:dkey-72g4.2
- zgc:162523
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein-macromolecule adaptor activity. Acts upstream of or within regulation of heart contraction. Predicted to be located in sarcoplasmic reticulum membrane. Predicted to be active in junctional sarcoplasmic reticulum membrane and plasma membrane. Is expressed in adaxial cell; cardiovascular system; musculature system; somite; and yolk syncytial layer. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia and catecholaminergic polymorphic ventricular tachycardia 5. Orthologous to human TRDN (triadin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6894188 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Vecchi et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| catecholaminergic polymorphic ventricular tachycardia 5 | Alliance | Cardiac arrhythmia syndrome, with or without skeletal muscle weakness | 615441 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR010798 | Triadin |
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers