ZFIN is now using GRCz12tu for Genomic Data
Gene
rfx6
- ID
- ZDB-GENE-041014-299
- Name
- regulatory factor X, 6
- Symbol
- rfx6 Nomenclature History
- Previous Names
-
- si:dkeyp-93d12.2
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endocrine pancreas development. Predicted to be located in nucleus. Is expressed in intestine; pancreas; pancreas primordium; and pancreatic bud. Orthologous to human RFX6 (regulatory factor X6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Soyer et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mitchell-Riley syndrome | 615710 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003150 | DNA-binding RFX-type winged-helix domain |
| Domain | IPR057321 | RFX1-4/6/8-like, BCD domain |
| Family | IPR039779 | RFX-like DNA-binding protein |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DNA-binding RFX-type winged-helix domain | RFX1-4/6/8-like, BCD domain | RFX-like DNA-binding protein | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PC03 | InterPro | 930 | |||||
| UniProtKB:Q5RJA1 | InterPro | 848 | |||||
| UniProtKB:A0AB13A9V3 | InterPro | 930 | |||||
| UniProtKB:A0AB32TDS4 | InterPro | 849 | |||||
| UniProtKB:A0AC58I361 | InterPro | 901 | |||||
| UniProtKB:A0AC58I366 | InterPro | 515 | |||||
| UniProtKB:A0AC58I379 | InterPro | 901 | |||||
| UniProtKB:A0AC58I380 | InterPro | 586 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers