ZFIN is now using GRCz12tu for Genomic Data
Gene
cyp3c3
- ID
- ZDB-GENE-041114-102
- Name
- cytochrome P450, family 3, subfamily c, polypeptide 3
- Symbol
- cyp3c3 Nomenclature History
- Previous Names
-
- cyp3c1l2 (1)
- zgc:101781
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including adaxial cell; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in essential hypertension; leukemia (multiple); and leukopenia (multiple). Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101781 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome P450 | Cytochrome P450 3A | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:E9QEE5 | InterPro | 503 | |||||
| UniProtKB:A0A8M6Z4Z2 | InterPro | 503 | |||||
| UniProtKB:A0AC58IPP3 | InterPro | 503 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp3c3-201
(1)
|
Ensembl | 2,225 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers