ZFIN is now using GRCz12tu for Genomic Data
Gene
kics2
- ID
- ZDB-GENE-041210-104
- Name
- KICSTOR subunit 2
- Symbol
- kics2 Nomenclature History
- Previous Names
-
- si:ch211-125a15.1
- zgc:136251
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in several processes, including cellular response to amino acid starvation; cellular response to glucose starvation; and negative regulation of TORC1 signaling. Predicted to be located in lysosomal membrane. Predicted to be part of KICSTOR complex. Orthologous to human KICS2 (KICSTOR subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Buchert et al., 2025
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Buchert et al., 2025
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 83 | Alliance | Intellectual developmental disorder, autosomal recessive 83 | 621100 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | KICSTOR complex protein C12orf66-like, central domain superfamily | KICSTOR subunit 2 |
|---|---|---|---|---|
| UniProtKB:B7ZUU9 | InterPro | 449 | ||
| UniProtKB:Q1L8F9 | InterPro | 449 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-125a15.1-201
(1)
|
Ensembl | 1,726 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers