Gene
unc119a2
- ID
- ZDB-GENE-050201-2
- Name
- unc-119 lipid binding chaperone a2
- Symbol
- unc119a2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable lipid binding activity. Acts upstream of or within Kupffer's vesicle development and visual perception. Predicted to be located in centrosome; cytoplasm; and spindle pole. Is expressed in several structures, including adaxial cell; central nervous system; renal system; solid lens vesicle; and visual system. Human ortholog(s) of this gene implicated in cone-rod dystrophy 24 and immunodeficiency 13. Orthologous to human UNC119 (unc-119 lipid binding chaperone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wright et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 24 | Alliance | Cone-rod dystrophy 24 | 620342 |
| immunodeficiency 13 | Alliance | ?Immunodeficiency 13 | 615518 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GMP phosphodiesterase, delta subunit | GMP phosphodiesterase, delta subunit superfamily | Immunoglobulin E-set | PDE6D/unc-119 myristoyl-binding |
|---|---|---|---|---|---|---|
| UniProtKB:Q1RM42 | InterPro | 264 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
unc119b-201
(1)
|
Ensembl | 2,239 nt |
Interactions and Pathways
No data available
Plasmids