stab1

ID

ZDB-GENE-050208-554

Name

stabilin 1

Symbol

stab1 Nomenclature History

Previous Names

stab1l
si:dkeyp-87e7.6

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Enables scavenger receptor activity. Acts upstream of or within several processes, including cholesterol homeostasis; low-density lipoprotein particle clearance; and oxidised low-density lipoprotein particle clearance. Predicted to be located in membrane. Is expressed in several structures, including axis; caudal hematopoietic tissue; pharynx; post-vent region; and vasculature. Orthologous to human STAB1 (stabilin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 7 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu453 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stab1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Hyperferritinemia]	620729

Associated With stab1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000538	Link domain
Domain	IPR000742	EGF-like domain
Domain	IPR000782	FAS1 domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR002049	Laminin-type EGF domain
Domain	IPR024731	EGF domain
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR036378	FAS1 domain superfamily